Announcement
Mavengity Expands into B2B Research
Owner Marko Pargo Ivanov is now writing the B2B Research desk directly, turning Forrester and Gartner category reports into plain-English breakdowns for buyers.
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Posted in the last 24 hours
Fresh from the desks
gene therapy
The First Treatment for Sanfilippo Syndrome Type A Arrived, and It Came as a Gene Therapy
The FDA approved Ultragenyx's Fayuvi, the first therapy for the fatal childhood disorder, on the strength of a single-arm trial compared against a natural history cohort, with the clearest benefit in children treated before regression.
election law
The Missouri Map Fight Reached the Appeals Court the Same Week Ballots Had to Mail
An Eighth Circuit panel heard Republican arguments to revive Missouri's 2025 congressional map, but the Supreme Court's stay and the Friday military-ballot deadline make the real decision a race against the calendar.
markets
The SEC Just Opened a Five-Year Door to Tokenized Stocks by Exemption, Not Legislation
A new SEC order lets trading venues issue tokenized versions of publicly traded U.S. stocks under a five-year exemption, with dividend and voting rights attached, two days after the Clarity Act failed in the Senate.
neurology
Novartis Halted Its ALS Drug After the Biomarkers Moved and the Patients Did Not
The Phase 2 ASTRALS trial of VHB937 missed both endpoints in 251 people with early ALS, ending the TREM2-targeting program and marking Novartis's fourth clinical setback in under a month.
women's health
Testosterone Prescriptions for Women Nearly Tripled While the FDA Had No Approved Product. The Review Just Opened
The FDA held a public workshop on testosterone therapy for menopausal women as prescriptions surged 146 percent in three years, and the central question is what evidence would be enough for the first approved product.
rates
The 30-Year Mortgage Jumped to 6.95 Percent in the Week the Fed Hiked
The average 30-year fixed mortgage rate rose 19 basis points this week to 6.95 percent, the market's fast repricing after the Federal Reserve's first hike in three years, and buyers are now credit-checked against the new level.
rates
Denmark Opened Its First 5 Percent Mortgage Since 2023, and the Fed Hike Helped Push It Open
Jyske Realkredit opened a 5 percent fixed-rate mortgage for the first time since December 2023 as rising oil prices, inflation expectations, and U.S. rates pushed the long-running 4 percent loan toward closure.
enforcement
Oregon's COVID Fraud Prosecutors Have Recovered 22 Cents on Every Stolen Dollar
The U.S. Attorney's Office in Oregon announced more than $314 million recovered from pandemic relief fraud, roughly a fifth of the $1.6 billion in alleged losses, as a national push races the statutes of limitations.
oncology
A Childhood Leukemia Trial Just Replaced Chemotherapy Instead of Adding to It
A 709-child trial published in the New England Journal of Medicine found that swapping two chemotherapy blocks for the immunotherapy blinatumomab nearly halved relapses while cutting severe infections from 69 to 24 percent.
B2B Research
Most Popular Research Articles
Intent Data
Intent Data Providers For B2B
Non-English intent signal is still under twenty percent of total volume industrywide, which means most platforms are seeing a fraction of the buying activity happening outside English language markets.
Knowledge Management
Knowledge Management Solutions
One vendor is explicitly competing on restraint, arguing that a plausible AI generated article that is subtly wrong is worse for a knowledge base than no article at all.
MDR
Managed Detection And Response Services
Forrester's own buyer guidance undercuts the AI pitch: providers are getting measurably more efficient, and there is little evidence yet that any of that efficiency is reaching customer pricing.
MDR Europe
Managed Detection And Response Services In Europe
Forrester's guidance to buyers is blunt: having a data centre in the EU answers one sovereignty question out of four, and most vendor pitches stop at the first.
Manufacturing Tech
Manufacturing Technology Services
Forrester frames 2026's binding constraint as a workforce that cannot be trained fast enough, which makes this a services category built around people more than platforms.
Market Intelligence
Market And Competitive Intelligence Platforms
Generative AI should have commoditized this category, and instead Forrester's criteria count kept climbing, because the moat was always licensed source access, not summarization.
Open Banking
Open Banking Intermediaries
Two of the category's most prominent independent players are now owned by the card networks they were supposed to route around.
Change Management
Organizational Change Management Services
Forrester's provider count nearly doubled in three years, and every other technology category in this series points at the same root cause: the software works and the organisation does not change.
PLM
Product Lifecycle Management Platforms For Discrete Manufacturers
Every reference customer for one vendor said they would buy again, which in PLM can mean genuine excellence or a customer base that has nowhere else to go once the evidence chain is built.
Announcements
News from Mavengity
Announcement
James T. Joins Mavengity as a Medical Writer
With James now writing full time for our Healthcare & Medical desk, Mavengity has formally expanded into dedicated medical authorship.
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