Hepatitis delta

Mirum's Hepatitis Delta Antibody Clears a Second Phase 3 Trial

Brelovitug met its primary endpoint in AZURE-4, with 59% and 44% of patients reaching combined virologic and liver-enzyme response at 24 weeks, setting up a 2027 FDA filing.

By James T.·November 10, 2026·9 min read

Rural health

CMS Releases $10 Billion in Rural Health Awards Without Explaining the Delay

CMS released $10 billion in second-year rural health awards nine days after its deadline, leaving the scoring formula and a new administrative requirement unexplained.

By James T.·November 10, 2026·9 min read

AI

Anthropic Ships Faster, Cheaper Models Into Its IPO Window

Anthropic launched Fable 5.2 and Mythos 5.2 a week before its expected IPO, pairing faster, cheaper models with an S-1 that shows a $567 million quarterly operating loss.

By Vasil V.·November 10, 2026·9 min read

Climate disclosure

The Ninth Circuit Splits California's Climate Disclosure Laws

A Ninth Circuit panel paused SB 261 and SB 253's Scope 3 reporting on First Amendment grounds while allowing Scope 1 and 2 disclosures to proceed.

By Victoria C.·November 9, 2026·9 min read

Stroke

A New Stroke Drug Class Starts With a Narrow Approval

The FDA approved Bayer's asundexian for secondary stroke prevention after a 12,327-patient trial cut recurrent ischemic stroke by 26% without a significant rise in major bleeding.

By James T.·November 9, 2026·9 min read

Drug safety

A Rare Eye Risk Joins the GLP-1 Label

The FDA ordered class-wide GLP-1 labeling changes for a rare optic-nerve condition, citing 15 probable cases in a meta-analysis of more than 134,000 patients.

By James T.·November 9, 2026·9 min read

Banking

UniCredit Moves From Stake to Control at Commerzbank

UniCredit plans to call a Commerzbank shareholder vote and remake the supervisory board after securing nearly 50% of voting rights, turning a long stake-building campaign into control.

By Vasil V.·November 9, 2026·9 min read

Drug pricing

Medicare's Drug Price Negotiation Program Gets a Permanent Rulebook

CMS finalized a rule codifying Medicare drug price negotiation from 2029, closing a reformulation loophole and setting a temporary floor for small biotech drugs.

By James T.·November 9, 2026·9 min read

Supreme Court

The Supreme Court Sends a Transgender Prison Case Back Down

The justices granted cert, vacated, and remanded Roybal v. Griffith in light of B.P.J. and Skrmetti, sending the 10th Circuit back to reconsider its standard for sex-based jail policies.

By Victoria C.·November 9, 2026·9 min read

Intent Data

Intent Data Providers For B2B

Non-English intent signal is still under twenty percent of total volume industrywide, which means most platforms are seeing a fraction of the buying activity happening outside English language markets.

By Marko P.·8 min read

Knowledge Management

Knowledge Management Solutions

One vendor is explicitly competing on restraint, arguing that a plausible AI generated article that is subtly wrong is worse for a knowledge base than no article at all.

By Marko P.·8 min read

MDR

Managed Detection And Response Services

Forrester's own buyer guidance undercuts the AI pitch: providers are getting measurably more efficient, and there is little evidence yet that any of that efficiency is reaching customer pricing.

By Marko P.·8 min read

MDR Europe

Managed Detection And Response Services In Europe

Forrester's guidance to buyers is blunt: having a data centre in the EU answers one sovereignty question out of four, and most vendor pitches stop at the first.

By Marko P.·8 min read

Manufacturing Tech

Manufacturing Technology Services

Forrester frames 2026's binding constraint as a workforce that cannot be trained fast enough, which makes this a services category built around people more than platforms.

By Marko P.·8 min read

Market Intelligence

Market And Competitive Intelligence Platforms

Forrester's Q3 2026 Wave scores ten providers against twenty nine criteria, cutting the field's criteria count for the first time, while a vendor that owns its content finishes last equal.

By Marko P.·10 min read

Open Banking

Open Banking Intermediaries

Two of the category's most prominent independent players are now owned by the card networks they were supposed to route around.

By Marko P.·8 min read

Change Management

Organizational Change Management Services

Forrester's provider count nearly doubled in three years, and every other technology category in this series points at the same root cause: the software works and the organisation does not change.

By Marko P.·8 min read

PLM

Product Lifecycle Management Platforms For Discrete Manufacturers

Every reference customer for one vendor said they would buy again, which in PLM can mean genuine excellence or a customer base that has nowhere else to go once the evidence chain is built.

By Marko P.·8 min read